Scientists, dermatologists, and aestheticians are always inventing and formulating various methods and products for anti-aging purposes. Today, we will get to know a unique ingredient that a few skincare companies are finally using to prevent those wrinkles, fine lines, and sagging of the skin: human stem cells.
In this article, we will discuss all about the sources, types, and usage of human stem cells and their role in preventing and treating skin aging.
Human Stem Cells — Sources, Types and Usage
According to an expert, stem cells refers to a rather broad category of cells that contribute in tissue generation, regeneration, and renewal. Simply, these are the cells that help us humans, animals, and plants heal. Also, this is what makes stem cells special: they have the much-coveted ability to divide to make more stem cells, and more stem cells.
Human stem cells are divided into three primary categories: embryonic, which are the initial stem cells after birth that control the development into a human baby; adult mesenchymel stem cells, which exist in our bodies and are responsible for the repair and renewal of structural tissues; and tissue-specific stem cells, which only repair and rejuvenate specific tissues such as your skin. Embryonic stem cells, stem cells from umbilical cord and tooth germs, and adult stem cells from bone marrow and other locations all offer potential sources for tissue repair.
Below are some details about the sources, types, and usage of human stem cells based on the article from Medical News Today.
1. Adult Stem Cells
Stem cells are present inside different types of tissue. Scientists have found stem cells in tissues, including:
2. Embryonic Stem Cells
Soon, and before the embryo implants in the uterus, this mass of around 150–200 cells is the blastocyst. The blastocyst consists of two parts:
The inner cell mass is where embryonic stem cells are found. Embryonic stem cells can differentiate into more cell types than adult stem cells.
3. Mesenchymal stem cells (MSCs)
MSCs come from the connective tissue or stroma that surrounds the body’s organs and other tissues.
Scientists have used MSCs to create new body tissues, such as bone, cartilage, and fat cells. They may one day play a role in solving a wide range of health problems.
4. Induced pluripotent stem cells (iPS)
Scientists create these in a lab, using skin cells and other tissue-specific cells. These cells behave in a similar way to embryonic stem cells, so they could be useful for developing a range of therapies. However, more research and development is necessary.
Totipotent: These stem cells can differentiate into all possible cell types. The first few cells that appear as the zygote starts to divide are totipotent.
Pluripotent: These cells can turn into almost any cell. Cells from the early embryo are pluripotent.
Multipotent: These cells can differentiate into a closely related family of cells. Adult hematopoietic stem cells, for example, can become red and white blood cells or platelets.
Oligopotent: These can differentiate into a few different cell types. Adult lymphoid or myeloid stem cells can do this.
Unipotent: These can only produce cells of one kind, which is their own type. However, these are still stem cells because they can renew themselves. Examples include adult muscle stem cells.
Due to a shortage of donor organs, scientists could use stem cells by instructing them to differentiate in a certain way, and to grow a specific tissue type or organ.
For example, doctors have already used stem cells from just beneath the skin’s surface to make new skin tissue. They can then repair a severe burn or another injury by grafting this tissue onto the damaged skin, and new skin will grow back.
Doctors now routinely use adult hematopoietic stem cells to treat diseases, such as leukemia, sickle cell anemia, and other immunodeficiency problems.
Hematopoietic stem cells occur in blood and bone marrow and can produce all blood cell types, including red blood cells that carry oxygen and white blood cells that fight disease.
The Role of Human Stem Cells in Preventing and Treating Skin Aging
Two processes result in the skin changes associated with aging. Chronological aging has strong genetic influences and includes the effects of gravity, sleep lines, expression lines, hormonal changes, and atrophy. The second process is extrinsic aging, the accumulation of a lifetime of effects from environmental influences such as ultraviolet and chemical exposure.
Based on the book “A Roadmap to Nonhematopoietic Stem Cell-Based Therapeutics”, human embryonic stem cells exhibit unlimited self renewal and the capacity to differentiate into three germ layer-origin tissues. But this type of cells have many challenges to consider. To resolve these challenges, induced pluripotent stem cells are created from somatic cells to be used in several human therapies. But mesenchymal stem cells (MSCs) are the only preferable type of stem cells to be used right now due to biosafety concerns.
For skin regenerative and renewal purposes, stem cells are indeed useful and effective components in preventing and treating signs of aging. We are glad that our RE Placenta Serum contains human-derived stem cells extracted from the dental pulp. Try our new anti-aging product right now!
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